Desitin is a thick, white cream that helps soothe and protect chafed skin due to diaper rash. The zinc oxide in Desitin provides a protective barrier to block moisture and soothe irritated skin. It is often recommended by pediatricians and parents for its effectiveness in preventing and treating diaper rash. Desitin is easy to apply and is typically used at each diaper change to provide continuous protection. It is important to clean and dry the diaper area thoroughly before applying Desitin for best results.